Revolutionizing Healthcare: Unleashing the Potential of Stem Cell Therapy

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  Stem Cell Therapy In recent years, the field of healthcare has been witnessing a revolutionary approach with the advent of stem cell therapy. Stem cell therapy holds immense promise in treating a wide range of medical conditions and has the potential to revolutionize the way we approach healthcare. This cutting-edge therapy utilizes the remarkable abilities of stem cells to repair and regenerate damaged tissues, offering new hope for patients suffering from debilitating diseases and injuries. Stem cells are undifferentiated cells that have the unique ability to develop into specialized cell types in the body. They can be derived from various sources, including embryos, umbilical cord blood, and adult tissues such as bone marrow and adipose tissue. This versatility of stem cells makes them a valuable tool in regenerative medicine. One of the most promising applications of Stem Cell Therapy is in the treatment of degenerative diseases such as Parkinson's disease, Alzheimer'
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Glycated albumin: A Potential Biomarker in Diabetes

GA is the higher glycated portion of fructosamine



Diabetes mellitus (DM) is a chronic and metabolic condition that affects a large number of people across the world. The reference test for long-term glucose monitoring is glycated haemoglobin (A1C), which has been linked to diabetes chronic problems. However, in clinical circumstances when haemoglobin metabolism may be hampered, such as hemolytic, secondary, or iron deficiency anaemia, hemoglobinopathies, pregnancy, and uremia, A1C is not advised. Glycated albumin (GA) is a test that measures short-term glycemia and is unaffected by circumstances that modify A1C levels artificially.


GA is the higher glycated portion of fructosamine. It is assessed using a standardised enzymatic approach that is simple and quick to implement. Because of these laboratory features, Glycated albumin has been highlighted in research over the last decade as a marker for DM monitoring and screening, as well as a predictor of long-term disease outcomes. The purpose of this review was to go over the physiological and biochemical properties of the GA, as well as its therapeutic usefulness in DM.


Albumin is a 66.7 kDa high molecular weight protein made up of a single polypeptide chain with 585 amino acids, 17 disulfide bridges, and three homologous domains linked in a helical shape. It is the most abundant plasma protein, accounting for around 60% of all proteins in the blood, with concentrations ranging from 3.0 to 5.0 g/dL and a half-life of 14 to 20 days. Albumin's shape makes it easier for it to conduct physiological activities including pH regulation and blood osmotic pressure regulation. Albumin also functions as an antioxidant and the primary transporter of metabolic products, ions, minerals, medicines, hormones, and fatty acids.

Albumin is a key transporter of lipids, metal ions, and amino acids and is essential for physiological activities. It has antioxidant properties and also binds to medicines. An albumin gene mutation has been linked to Analbuminemia, an autosomal recessive disease characterised by low albumin levels. In albumin, lysine 525 is the main glycation site. Glycated albumin is a glycemic marker that may be used to measure HbA1c-based glycemic management in diabetic individuals.

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