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Biological Safety Cabinets |
Biological safety cabinets, also known as microbiological safety cabinet or biosafety cabinets, are one type of bio-containment equipment used in biological laboratories to provide personnel, environmental, and product protection. These cabinets are designed for laboratory operators to safely work with contaminated or biohazard materials. Biological safety cabinets are divided into three classes, such as Class I, Class I and Class III. Class I provides protection for the user and surrounding environment. Class II provides protection for the user, environment, and the sample, and is subdivided into four types, such as A1, A2, B1 and B2.
Class III is designed to work with highly infectious agents and provides the highest level of protection for the user, environment, and sample.
Biological safety cabinets provide different levels of protection to obtain optimum control over product quality by reducing potential risk of exposure to biohazards materials. Thus, with the rapid growth in the number of biologics and increased risk of pandemics and communicable diseases, the demand for biological safety cabinets is also increasing. For example, according to the World Health Organization (WHO), In the United States, as of 8 November 2021, there have been 46,146,676 confirmed cases of COVID-19, including 747,957 deaths.
Laboratory biosafety guidelines issued by both WHO and CDC provide guidance on the safe handling of COVID-19 samples within clinical and research laboratories. The CDC and WHO recommend that Class II Cabinets (BSCs) be utilized any time a laboratory has the potential to generate aerosols or droplets as result of vortexing, pipetting, centrifugation, or other laboratory techniques. Laboratories carrying out COVID-19 testing must have the appropriate equipment and facility to protect lab personnel. Thus, CDC and WHO recommends handling COVID-19 samples in a properly maintained and certified Class II Biological Safety Cabinets (BSCs).
Biosafety cabinets can be classified on the basis of construction, velocity, air flow pattern, and exhaust system and are equipped with high-efficiency particulate arrest filters, which help to maintain the sterility of the environment from biohazard materials.
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